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PALMITOYL PENTAPEPTIDE-4

SKU: P100015
Palmitoyl Pentapeptide-4 is a synthetic biomimetic peptide engineered to mimic the natural skin-repairing fragments of elastin and collagen. As one of the most researched "matrikine" signal peptides, it penetrates the stratum corneum to deliver potent anti-aging benefits at the cellular level.
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  • PALMITOYL PENTAPEPTIDE-4
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The Clinically Proven Signal Peptide for Collagen Regeneration

Palmitoyl Pentapeptide-4 is a synthetic biomimetic peptide engineered to mimic the natural skin-repairing fragments of elastin and collagen. As one of the most researched "matrikine" signal peptides, it penetrates the stratum corneum to deliver potent anti-aging benefits at the cellular level.

By binding to specific receptors on fibroblasts, Palmitoyl Pentapeptide-4 triggers the skin’s own repair mechanism—stimulating the production of Type I, III, and IV collagenfibronectin, and hyaluronic acid. The result is a visible reduction in fine lines, improved skin firmness, and enhanced elasticity.

Key Benefits:

  • Reduces wrinkle depth (especially around eyes and mouth) within 4–8 weeks of consistent use.

  • Restores skin density without irritation, making it ideal for sensitive or retinoid-intolerant skin.

  • Strengthens the dermal-epidermal junction to prevent transepidermal water loss (TEWL).

  • Synergistic with retinol, vitamin C, and hyaluronic acid for advanced anti-aging formulations.

Typical Use: 0.5% – 5% concentration in serums, creams, eye contour products, and masks (pH 5–7 recommended).

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